Structure of PDB 9b6e Chain D

Receptor sequence
>9b6eD (length=929) Species: 10090 (Mus musculus) [Search protein sequence]
DLVNFIQANFDAFGDIQFGKYLRLSCDTDSETLYELLTQHWHLKTPNLVI
SVTGGAKNFALKPRMRKIFSRLIYIAQSKGAWILTGGTHYGLMKYIGEVV
RDNTISENIVAIGIAAWGMVSNRDTLFSAQYIMLYILDNNHTHLLLVDNG
CHGHPTVEAKLRNQLEKYISERTSQDSNYGGKIPIVCFAQGGGRETLKAI
NTSVKSKIPCVVVEGSGQIADVIASLVTSSMVKEKLVRFLPRTVSRLPEE
EIESWIKWLKEILESSHLLTVIKMEEAGDEIVSNAISYALYKAFSTNEQD
KDNWNGQLKLLLEWNQLDLASDEIFTNDRRWESADLQEVMFTALIKDRPK
FVRLFLENGLNLQKFLTNEVLTELFSTHFSTLVYRNLQIAKNSYNDALLT
FVWKLVANFRRSTRHPLQALFIWAILQNKKELSKVIWEQTKGCTLAALGA
SKLLKTLAKVKNDINAAGESEELANEYETRAVELFTECYSNDEDLAEQLL
VYSCEAWGGSNCLELAVEATDQHFIAQPGVQNFLSKQWYGEISRDTKNWK
IILCLFIIPLVGCGLVSFRKLWYYVAFFTSPFVVFSWNVVFYIAFLLLFA
YVLLMDFHSVPHTPELILYALVFVLFCDEVRQWYMNGVNYFTDLWNVMDT
LGLFYFIAGIVFRLHSSNKSSLYSGRVIFCLDYIIFTLRLIHIFTVSRNL
GPKIIMLQRMLIDVFFFLFLFAVWMVAFGVARQGILRQNEQRWRWIFRSV
IYEPYLAMFGQVPSDVDSTTYDFSHCTFSGNESKPLCVELDEHNLPRFPE
WITIPLVCIYMLSTNILLVNLLVAMFGYTVGIVQENNDQVWKFQRYFLVQ
EYCNRLNIPFPFVVFAYFYMVVKKNETLAWEGVMKENYLVKINTKANDNS
EEMRHRFRQLDSKLNDLKSLLKEIANNIK
3D structure
PDB9b6e Mechanisms of sensory adaptation and inhibition of the cold and menthol receptor TRPM8.
ChainD
Resolution2.91 Å
3D
structure
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Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 T14 D W877 S966 W724 S813
BS02 Y01 D I696 V743 V849 I552 V590 V696
External links
PDB RCSB:9b6e, PDBe:9b6e, PDBj:9b6e
PDBsum9b6e
PubMed39093967
UniProtQ8R4D5|TRPM8_MOUSE Transient receptor potential cation channel subfamily M member 8 (Gene Name=Trpm8)

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