Structure of PDB 9at2 Chain D

Receptor sequence

>9at2D (length=342) Species: 9606 (Homo sapiens) [Search protein sequence]

LIYGNYLHLEKVLNAQELQSETKGNKIHDEHLFIITHQAYELWFKQILWE
LDSVREIFQNGHVRDERNMLKVVSRMHRVSVILKLLVQQFSILETMTALD
FNDFREYLSPASGFQSLQFRLLENKIGVLQNMRVPYNRRHYRDNFKGEEN
ELLLKSEQEKTLLELVEAWLERTPGLEPHGFNFWGKLEKNITRGLEEEFI
RIQAKEESEEKEEQVAEFQKQKEVLLSLFDEKRHEHLLSKGERRLSYRAL
QGALMIYFYREEPRFQVPFQLLTSLMDIDSLMTKWRYNHVCMVHRMLGSG
YHYLRSTVSDRYKVFVDLFNLSTYLIPRHWIPKMNPTIHKFL

3D structure

PDB

9at2 Structural Insights into Protein-Inhibitor Interactions in Human Tryptophan Dioxygenase.

Chain

Resolution

2.25 Å

3D
structure

[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)
BS01	A1AF5	D	Y42 Y45	Y3 Y6
BS02	HEM	D	F72 H76 Y79 S151 G152 F153 F158 R159 Y175 H328 M331 V332 Y350 L351	F33 H37 Y40 S112 G113 F114 F119 R120 Y136 H289 M292 V293 Y303 L304
BS03	ZIQ	D	R103 E105 W208 R211 P213 F304 P307	R64 E66 W169 R172 P174 F265 P268
BS04	A1AF5	D	F72 H76 R144 S148 A150	F33 H37 R105 S109 A111

External links

PDB	RCSB:9at2, PDBe:9at2, PDBj:9at2
PDBsum	9at2
PubMed	39106326
UniProt	P48775\|T23O_HUMAN Tryptophan 2,3-dioxygenase (Gene Name=TDO2)

[Back to BioLiP]