Structure of PDB 8zv9 Chain D

Receptor sequence

>8zv9D (length=278) Species: 9606 (Homo sapiens) [Search protein sequence]

DGSHSMRYFSTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRA
PWIEQEGPEYWDEETGKVKAHSQTDRENLRIALRYYNQSEAGSHTLQMMF
GCDVGSDGRFLRGYHQYAYDGKDYIALKEDLRSWTAADMAAQITKRKWEA
AHVAEQQRAYLEGTCVDGLRRYLENGKETLQRTDPPKTHMTHHPISDHEA
TLRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVV
PSGEEQRYTCHVQHEGLPKPLTLRWEPG

3D structure

PDB

8zv9 Structural insights into immune escape at killer T cell epitope by SARS-CoV-2 Spike Y453F variants.

Chain

Resolution

2.6 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	peptide	D	D220 G221 R273	D221 G222 R274
BS02	peptide	D	Y7 E63 K66 V67 H70 T73 N77 I80 Y84 L95 F99 Y116 Y123 T143 K146 W147 Q155 Q156 Y159 T163 Y171	Y8 E64 K67 V68 H71 T74 N78 I81 Y85 L96 F100 Y117 Y124 T144 K147 W148 Q156 Q157 Y160 T164 Y172

External links

PDB	RCSB:8zv9, PDBe:8zv9, PDBj:8zv9
PDBsum	8zv9
PubMed	39002680
UniProt	A0A7T3RIT5

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