Structure of PDB 8yvp Chain D

Receptor sequence
>8yvpD (length=199) Species: 10090 (Mus musculus) [Search protein sequence]
TTLAFKFLHGVIVAADSRATAGAYIASQTVKKVIEINPYLLGTMAGGAAD
CSFWERLLARQCRIYELRNKERISVAAASKLLANMVYQYKGMGLSMGTMI
CGWDKRGPGLYYVDSEGNRISGTAFSVGSGSVYAYGVMDRGYSYDLKVEE
AYDLARRAIYQATYRDAYSGGAVNLYHVREDGWIRVSSDNVADLHDKYS
3D structure
PDB8yvp Optimization of alpha-amido boronic acids via cryo-electron microscopy analysis: Discovery of a novel highly selective immunoproteasome subunit LMP7 ( beta 5i)/LMP2 ( beta 1i) dual inhibitor.
ChainD
Resolution2.5 Å
3D
structure
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Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 A1L0D D L58 R61 Y90 L57 R60 Y89
BS02 A1L0D D T2 D17 A20 T21 A22 V31 K33 M45 G47 A49 G129 S130 S170 T1 D16 A19 T20 A21 V30 K32 M44 G46 A48 G128 S129 S169
External links
PDB RCSB:8yvp, PDBe:8yvp, PDBj:8yvp
PDBsum8yvp
PubMed38906067
UniProtO55234|PSB5_MOUSE Proteasome subunit beta type-5 (Gene Name=Psmb5)

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