Structure of PDB 8ysx Chain D

Receptor sequence
>8ysxD (length=200) Species: 9615 (Canis lupus familiaris) [Search protein sequence]
TTLAFKFQHGVIVAVDSRATAGNYISSSRVNKVIEINPSLLGTMSGCAAD
CQYWERLLAKECRLYYLRNGERISVSAASKLLSNMVYQYRGMDLSMGSMI
CGWDKKGPGLYYVDQNGTRLSGNMFSTGSGSTYAYGVMDSGYQPSLSPEE
AYELGRRAITYATHRDSYSGGIINMYHMKEDGWVKVESTDVNELLHQYQE
3D structure
PDB8ysx Optimization of alpha-amido boronic acids via cryo-electron microscopy analysis: Discovery of a novel highly selective immunoproteasome subunit LMP7 ( beta 5i)/LMP2 ( beta 1i) dual inhibitor.
ChainD
Resolution2.2 Å
3D
structure
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Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 A1L0D D T2 D17 A20 T21 K33 M45 S46 G47 A49 G129 S130 Y169 S170 T1 D16 A19 T20 K32 M44 S45 G46 A48 G128 S129 Y168 S169
External links
PDB RCSB:8ysx, PDBe:8ysx, PDBj:8ysx
PDBsum8ysx
PubMed38906067
UniProtQ5W416|PSB8_CANLF Proteasome subunit beta type-8 (Gene Name=PSMB8)

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