Structure of PDB 8yha Chain D

Receptor sequence

>8yhaD (length=355) Species: 1852835 (Candidatus Cloacimonetes bacterium ADurb.Bin088) [Search protein sequence]

MLIEIHMIQNHSPANLNRDDLGAPKTCYFGGVLRSRISSQCIKRSIRTSN
DFKALLGGVRTRRLADLIQQEAGETECWKKAQEILNKCGFKNKDDNTKML
VFMSKDKIKDLARIVLDNSLGLTEAAQQVANVIAQATLAPDIALCGRMLE
PNDKDKDKKVKWSNTTVEAALQVAHAISTHIARPEIDYFFASACFYKYFS
IDWEQLVKNLKGDTNLAAHTVGAFLLAAAKTNPSGKQNSFAAHNYPDGIL
VEFKNSPISYANAFVRPVSVVKESDLVEQSIGQLSNYVNDIRLGYYDEQS
PVIGFWFSPNNRYPLGYKHSKLASRNIGNLNELVGAVLDYIGGFKWEEVQ
KSKAY

3D structure

PDB

8yha Mechanisms for HNH-mediated target DNA cleavage in type I CRISPR-Cas systems

Chain

Resolution

3.4 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	D	N17 D20 Q40 C41 K43 R44 M148 G255 K256	N17 D20 Q40 C41 K43 R44 M148 G235 K236
BS02	dna	D	R62 K98 M99 M148 D153	R62 K98 M99 M148 D153

External links

PDB	RCSB:8yha, PDBe:8yha, PDBj:8yha
PDBsum	8yha
PubMed	39047725
UniProt	A0A1V6F8B5

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