Structure of PDB 8xfc Chain D

Receptor sequence
>8xfcD (length=517) Species: 83332 (Mycobacterium tuberculosis H37Rv) [Search protein sequence]
AAPLLSVEGLEVTFGTDAPAVCGVDLAVRSGQTVAVVGESGSGKSTTAAA
ILGLLPAGGRITAGRVVFDGRDITGADAKRLRSIRGREIGYVPQDPMTNL
NPVWKVGFQVTEALRANTDGRAARRRAVELLAEAGLPDPAKQAGRYPHQL
SGGMCQRALIAIGLAGRPRLLIADQPTSALDVTVQRQVLDHLQGLTDELG
TALLLITHDLALAAQRAEAVVVVRRGVVVESGAAQSILQSPQHEYTRRLV
AAAPSLGDILVVSELTKIYRESRGAPWRRVESRAVDGVSFRLPRASTLAI
VGESGSGKSTLARMVLGLLQPTSGTVVFDGTYDVGALARDQVLAFRRRVQ
PVFQNPYSSLDPMYSVFRAIEEPLRVHHVGDRRQRQRAVRELVDQVALPS
SILGRRPRELSGGQRQRVAIARALALRPEVLVCDQAVSALDVLVQAQILD
LLADLQADLGLTYLFISHDLAVIRQIADDVLVMRAGRVVEHASTEEVFSR
PRHEYTRQLLQAIPGAP
3D structure
PDB8xfc Cryo-EM structure of the ATP-bound Mtb DppABCD with the D445A mutation of DppA
ChainD
Resolution3.89 Å
3D
structure
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Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 ATP D Y291 G327 G329 K330 S331 Y269 G305 G307 K308 S309
BS02 ATP D F18 G45 S46 G47 K48 S49 T50 Q179 F14 G41 S42 G43 K44 S45 T46 Q175
External links