Structure of PDB 8x6g Chain D

Receptor sequence
>8x6gD (length=1176) Species: 1280 (Staphylococcus aureus) [Search protein sequence]
DVNNFHYMKIGLASPEKIRSWSFGEVKKPETINYRTLKPEKDGLFCERIF
GPTKDWECSCGKYKRVRYKGMVCDRCGVEVTKSKVRRERMGHIELAAPVS
HIWYFKGIPSRMGLLLDMSPRALEEVIYFASYVVVDPGPTGLEKKTLLSE
AEFRDYYDKYPGQFVAKMGAEGIKDLLEEIDLDEELKLLRDELESATGQR
LTRAIKRLEVVESFRNSGNKPSWMILDVLPIIPPEIRPMVQLDGGRFATS
DLNDLYRRVINRNNRLKRLLDLGAPGIIVQNEKRMLQEAVDALIDNGRRG
RPVTGPGNRPLKSLSHMLKGKQGRFRQNLLGKRVDYSGRSVIAVGPSLKM
YQCGLPKEMALELFKPFVMKELVQREIATNIKNAKSKIERMDDEVWDVLE
EVIREHPVLLNRAPTLHRLGIQAFEPTLVEGRAIRLHPLVTTAYNADFDG
DQMAVHVPLSKEAQAEARMLMLAAQNILNPKDGKPVVTPSQDMVLGNYYL
TLERKDAVNTGAIFNNTNEVLKAYANGFVHLHTRIGVHASSFNNPTFTEE
QNKKILATSVGKIIFNEIIPDSFAYINEPTQENLERKTPNRYFIDPTTLG
EGGLKEYFENEELIEPFNKKFLGNIIAEVFNRFSITDTSMMLDRMKDLGF
KFSSKAGITVGVADIVVLPDKQQILDEHEKLVDRITKQFNRGLITEEERY
NAVVEIWTDAKDQIQGELMQSLDKTNPIFMMSDSGARGNASNFTQLAGMR
GLMAAPSGKIIELPITSSFREGLTVLEYFISTHGARKGLADTALKTADSG
YLTRRLVDVAQDVIVREEDCGTDRGLLVSDIKEGTEMIEPFIERIEGRYS
KETIRHPETDEIIIRPDELITPEIAKKITDAGIEQMYIRSAFTCNARHGV
CEKCYGKNLATGEKVEVGEAVGTIAAQSIGEPGTQLTQGLPRIQEIFEAR
NPKGQAVITEIEGVVEDIKLAKDRQQEIVVKGANETRSYLASGTSRIIVE
IGQPVQRGEVLTEGSIEPKNYLSVAGLNATESYLLKEVQKVYRMQGVEID
DKHVEVMVRQMLRKVRIIEAGDTKLLPGSLVDIHNFTDANREAFKHRKRP
ATAKPVLLGITKASLETESFLSAASFQETTRVLTDAAIKGKRDDLLGLKE
NVIIGKLIPAGTGMRRYSDVKYEKTA
3D structure
PDB8x6g Structural basis of promoter recognition by Staphylococcus aureus RNA polymerase
ChainD
Resolution3.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.6: DNA-directed RNA polymerase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna D Q1144 E1145 Q1127 E1128
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0003677 DNA binding
GO:0003899 DNA-directed 5'-3' RNA polymerase activity
GO:0008270 zinc ion binding
GO:0016779 nucleotidyltransferase activity
GO:0034062 5'-3' RNA polymerase activity
GO:0046872 metal ion binding
Biological Process
GO:0006351 DNA-templated transcription
Cellular Component
GO:0000428 DNA-directed RNA polymerase complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8x6g, PDBe:8x6g, PDBj:8x6g
PDBsum8x6g
PubMed38844782
UniProtQ2G0N5|RPOC_STAA8 DNA-directed RNA polymerase subunit beta' (Gene Name=rpoC)

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