Structure of PDB 8w8g Chain D

Receptor sequence
>8w8gD (length=196) Species: 9606 (Homo sapiens) [Search protein sequence]
EDAGLVAEAEAVAAGWMLDFLCLSLCRAFRDGRSEDFRRTRNSAEAIIHG
LSSLTACQLRTIYICQFLTRIAAGKTLDAQFENDERITPLESALMIWGSI
EKEHDKLHEEIQNLIKIQAIAVCMENGNFKEAEEVFERIFFKSKLLMIIS
QKDTFHSFFQHFSYNHMMEKIKSYVNYVLSEKSSTFLMKAAAKVVE
3D structure
PDB8w8g PinX1 suppress tumorigenesis through inhibiting telomerase activity
ChainD
Resolution2.7 Å
3D
structure
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Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide D R99 R100 R38 R39
BS02 peptide D R102 N103 E106 I109 H110 L120 I123 Q127 R131 L138 D139 Q141 F142 E146 R147 I148 T149 R41 N42 E45 I48 H49 L59 I62 Q66 R70 L77 D78 Q80 F81 E85 R86 I87 T88
External links
PDB RCSB:8w8g, PDBe:8w8g, PDBj:8w8g
PDBsum8w8g
PubMed
UniProtP54274|TERF1_HUMAN Telomeric repeat-binding factor 1 (Gene Name=TERF1)

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