Structure of PDB 8w7e Chain D

Receptor sequence
>8w7eD (length=176) Species: 9606 (Homo sapiens) [Search protein sequence]
LIPIVVEQERAYDIYSRLLRERIVCVMGPIDDSVASLVIAQLLFLQSESN
KKPIHMYINSPGGVVTAGLAIYDTMQYILNPICTWCVGQAASMGSLLLAA
GTPGMRHSLPNSRIMIHQPSAIQAEEIMKLKKQLYNIYAKHTKQSLQVIE
SAMERDRYMSPMEAQEFGILDKVLVH
3D structure
PDB8w7e Design, synthesis and biological evaluations of novel small molecular hyper-activators of human caseinolytic peptidase P (hClpP)
ChainD
Resolution2.8 Å
3D
structure
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Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 9I3 D L104 F105 T135 Y138 L43 F44 T74 Y77
BS02 9I3 D L79 E82 I84 H116 Y118 W146 V148 L170 L18 E21 I23 H55 Y57 W85 V87 L109
External links
PDB RCSB:8w7e, PDBe:8w7e, PDBj:8w7e
PDBsum8w7e
PubMed
UniProtQ16740|CLPP_HUMAN ATP-dependent Clp protease proteolytic subunit, mitochondrial (Gene Name=CLPP)

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