Structure of PDB 8w7c Chain D

Receptor sequence
>8w7cD (length=175) Species: 9606 (Homo sapiens) [Search protein sequence]
SLIPIVVDIYSRLLRERIVCVMGPIDDSVASLVIAQLLFLQSESNKKPIH
MYINSPGGVVTAGLAIYDTMQYILNPICTWCVGQAASMGSLLLAAGTPGM
RHSLPNSRIMIHQPSATDIAIQAEEIMKLKKQLYNIYAKHTKQSLQVIES
AMERDRYMSPMEAQEFGILDKVLVH
3D structure
PDB8w7c Activation of mitochondrial Caseinolytic Protease P (ClpP) induces selective cancer cell lethality
ChainD
Resolution3.0 Å
3D
structure
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Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 R89 D L104 F105 S108 T135 Y138 L38 F39 S42 T69 Y72
BS02 R89 D R78 L79 E82 H116 Y118 W146 V148 R12 L13 E16 H50 Y52 W80 V82
External links
PDB RCSB:8w7c, PDBe:8w7c, PDBj:8w7c
PDBsum8w7c
PubMed
UniProtQ16740|CLPP_HUMAN ATP-dependent Clp protease proteolytic subunit, mitochondrial (Gene Name=CLPP)

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