Structure of PDB 8vz1 Chain D

Receptor sequence
>8vz1D (length=224) Species: 9606 (Homo sapiens) [Search protein sequence]
SLALSLTADQMVSALLDAEPPILYSEYSMMGLLTNLADRELVHMINWAKR
VPGFVDLTSHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRN
QGGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFKSLEEK
DHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGM
EHLYSMKCKNVVPSYDLLLEMLDA
3D structure
PDB8vz1 Asymmetric allostery in estrogen receptor-alpha homodimers drives responses to the ensemble of estrogens in the hormonal milieu.
ChainD
Resolution1.82 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 A1AHS D T347 A350 E353 L387 M388 I424 F425 G521 H524 T34 A37 E40 L74 M75 I107 F108 G199 H202
External links
PDB RCSB:8vz1, PDBe:8vz1, PDBj:8vz1
PDBsum8vz1
PubMed38830107
UniProtP03372|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)

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