Structure of PDB 8vz0 Chain D

Receptor sequence
>8vz0D (length=223) Species: 9606 (Homo sapiens) [Search protein sequence]
SLALSLTADQMVSALLDAEPPILYSEEASMMGLLTNLADRELVHMINWAK
RVPGFVDLTSHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDR
NQGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLSSTLK
SLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHM
SNKGMEHLYNVVPSYDLLLEMLD
3D structure
PDB8vz0 Asymmetric allostery in estrogen receptor-alpha homodimers drives responses to the ensemble of estrogens in the hormonal milieu.
ChainD
Resolution1.86 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 A1AHO D M343 T347 E353 L387 M388 F404 G521 L525 V533 M31 T35 E41 L75 M76 F92 G204 L208 V211
External links
PDB RCSB:8vz0, PDBe:8vz0, PDBj:8vz0
PDBsum8vz0
PubMed38830107
UniProtP03372|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)

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