Structure of PDB 8vyt Chain D

Receptor sequence
>8vytD (length=224) Species: 9606 (Homo sapiens) [Search protein sequence]
SLALSLTADQMVSALLDAEPPILYSESMMGLLTNLADRELVHMINWAKRV
PGFVDLTSHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQ
GMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSL
EEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSN
KGMEHLYKCKNVVPSYDLLLEMLD
3D structure
PDB8vyt Asymmetric allostery in estrogen receptor-alpha homodimers drives responses to the ensemble of estrogens in the hormonal milieu.
ChainD
Resolution1.61 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 A1AHV D T347 E353 L387 F404 H524 L525 T33 E39 L73 F90 H205 L206
External links
PDB RCSB:8vyt, PDBe:8vyt, PDBj:8vyt
PDBsum8vyt
PubMed38830107
UniProtP03372|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)

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