Structure of PDB 8vrn Chain D

Receptor sequence
>8vrnD (length=338) Species: 9606 (Homo sapiens) [Search protein sequence]
DNTTVFTRILDRLLDGYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDME
YTIDVFFRQSWKDERLKFKGPMTVLRLNNLMASKIWTPDTFFHNGKKSVA
HNMTMPNKLLRITEDGTLLYTMRLTVRAECPMHLEDFPMDAHACPLKFGS
YAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLLGQTVDSGIVQSSTGE
YVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFG
VTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNY
FTKSQPARAAKIDRLSRIAFPLLFGIFNLVYWATYLNR
3D structure
PDB8vrn Structural insights into GABA A receptor potentiation by Quaalude.
ChainD
Resolution2.57 Å
3D
structure
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Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 MAN D A109 N111 K117 A100 N102 K108
BS02 ABU D F65 R67 T130 F56 R58 T121
BS03 A1ADN D I228 L232 P233 T265 I219 L223 P224 T256
BS04 Q3G D F296 S299 R317 I321 F329 F287 S290 R308 I312 F320
External links
PDB RCSB:8vrn, PDBe:8vrn, PDBj:8vrn
PDBsum8vrn
PubMed38898000
UniProtP14867|GBRA1_HUMAN Gamma-aminobutyric acid receptor subunit alpha-1 (Gene Name=GABRA1)

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