Structure of PDB 8vqy Chain D

Receptor sequence
>8vqyD (length=338) Species: 9606 (Homo sapiens) [Search protein sequence]
DNTTVFTRILDRLLDGYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDME
YTIDVFFRQSWKDERLKFKGPMTVLRLNNLMASKIWTPDTFFHNGKKSVA
HNMTMPNKLLRITEDGTLLYTMRLTVRAECPMHLEDFPMDAHACPLKFGS
YAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLLGQTVDSGIVQSSTGE
YVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFG
VTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNY
FTKSQPARAAKIDRLSRIAFPLLFGIFNLVYWATYLNR
3D structure
PDB8vqy Structural insights into GABA A receptor potentiation by Quaalude.
ChainD
Resolution2.82 Å
3D
structure
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Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ABU D R67 T130 R58 T121
BS02 Q3G D F296 F298 S299 E303 R317 I321 S325 A328 F329 L332 F287 F289 S290 E294 R308 I312 S316 A319 F320 L323
BS03 A1ADG D Y160 V203 S205 Y210 Y151 V194 S196 Y201
External links
PDB RCSB:8vqy, PDBe:8vqy, PDBj:8vqy
PDBsum8vqy
PubMed38898000
UniProtP14867|GBRA1_HUMAN Gamma-aminobutyric acid receptor subunit alpha-1 (Gene Name=GABRA1)

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