Structure of PDB 8var Chain D

Receptor sequence
>8varD (length=360) Species: 562 (Escherichia coli) [Search protein sequence]
SYQVLARKWRPQTFADVVGQEHVLTALANGLSLGRIHHAYLFSGTRGVGK
TSIARLLAKGLNCETGITATPCGVCDNCREIEQGRFVDLIEIDAASRTKV
EDTRDLLDNVQYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEHVK
FLLATTDPQKLPVTILSRCLQFHLKALDVEQIRHQLEHILNEEHIAHEPR
ALQLLARAAEGSLRDALSLTDQAIASGDGQVSTQAVSAMLGTLDDDQALS
LVEAMVEANGERVMALINEAAARGIEWEALLVEMLGLLHRIAMVQLSPAA
LGNDMAAIELRMRELARTIPPTDIQLYYQTLLIGRKELPYAPDRRMGVEM
TLLRALAFHP
3D structure
PDB8var Differences between bacteria and eukaryotes in clamp loader mechanism, a conserved process underlying DNA replication.
ChainD
Resolution3.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.7: DNA-directed DNA polymerase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna D T99 K100 V101 R105 S132 T98 K99 V100 R104 S131
BS02 ZN D C64 C73 C76 C79 C63 C72 C75 C78
BS03 ADP D A7 R11 P12 V19 V49 G50 K51 T52 S53 L214 R215 A6 R10 P11 V18 V48 G49 K50 T51 S52 L213 R214
BS04 BEF D K51 R215 K50 R214
BS05 MG D T52 D126 T51 D125
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003887 DNA-directed DNA polymerase activity
GO:0005524 ATP binding
GO:0016887 ATP hydrolysis activity
Biological Process
GO:0006260 DNA replication
Cellular Component
GO:0009360 DNA polymerase III complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8var, PDBe:8var, PDBj:8var
PDBsum8var
PubMed38490435
UniProtP06710|DPO3X_ECOLI DNA polymerase III subunit tau (Gene Name=dnaX)

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