Structure of PDB 8val Chain D

Receptor sequence
>8valD (length=366) Species: 562 (Escherichia coli) [Search protein sequence]
GPHMSYQVLARKWRPQTFADVVGQEHVLTALANGLSLGRIHHAYLFSGTR
GVGKTSIARLLAKGLNCETGITATPCGVCDNCREIEQGRFVDLIEIDAAS
RTKVEDTRDLLDNVQYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPP
EHVKFLLATTDPQKLPVTILSRCLQFHLKALDVEQIRHQLEHILNEEHIA
HEPRALQLLARAAEGSLRDALSLTDQAIASGDGQVSTQAVSAMLGTLDDD
QALSLVEAMVEANGERVMALINEAAARGIEWEALLVEMLGLLHRIAMVQL
SPAALGNDMAAIELRMRELARTIPPTDIQLYYQTLLIGRKELPYAPDRRM
GVEMTLLRALAFHPRM
3D structure
PDB8val Differences between bacteria and eukaryotes in clamp loader mechanism, a conserved process underlying DNA replication.
ChainD
Resolution3.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.7: DNA-directed DNA polymerase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna D K100 V101 R105 S132 H134 K103 V104 R108 S135 H137
BS02 BEF D E144 R169 E147 R172
BS03 ZN D C76 C79 C79 C82
BS04 ADP D A7 W10 R11 P12 V18 V19 G48 V49 G50 K51 T52 S53 L214 R215 A10 W13 R14 P15 V21 V22 G51 V52 G53 K54 T55 S56 L217 R218
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003887 DNA-directed DNA polymerase activity
GO:0005524 ATP binding
GO:0016887 ATP hydrolysis activity
Biological Process
GO:0006260 DNA replication
Cellular Component
GO:0009360 DNA polymerase III complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8val, PDBe:8val, PDBj:8val
PDBsum8val
PubMed38490435
UniProtP06710|DPO3X_ECOLI DNA polymerase III subunit tau (Gene Name=dnaX)

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