Structure of PDB 8v30 Chain D

Receptor sequence
>8v30D (length=372) Species: 9606 (Homo sapiens) [Search protein sequence]
ETTALVCDNGSGLCKAGFAGDDAPRAVFPSIVGRPCHQGVMVGMGQKDSY
VGDEAQSKRGILTLKYPIEHGIITNWDDMEKIWHHSFYNELRVAPEEHPT
LLTEAPLNPKANREKMTQIMFETFNVPAMYVAIQAVLSLYASGRTTGIVL
DSGDGVTHNVPIYEGYALPHAIMRLDLAGRDLTDYLMKILTERGYSFVTT
AEREIVRDIKEKLCYVALDFENEMATAASSSSLEKSYELPDGQVITIGNE
RFRCPETLFQPSFIGMESAGIHETTYNSIMKCDIDIRKDLYANNVLSGGT
TMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQ
QMWISKPEYDEAGPSIVHRKCF
3D structure
PDB8v30 Molecular Mechanisms of ACTG2 Mutations Linked to Visceral Myopathy
ChainD
Resolution2.54 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 3.6.4.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide D T194 G197 Y198 S199 T191 G194 Y195 S196
BS02 peptide D E72 H73 I75 P112 E69 H70 I72 P109
BS03 ADP D G13 S14 G15 L16 K18 D157 K213 E214 G302 Y306 G10 S11 G12 L13 K15 D154 K210 E211 G299 Y303
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0016787 hydrolase activity
Biological Process
GO:0010628 positive regulation of gene expression
GO:0090131 mesenchyme migration
Cellular Component
GO:0005615 extracellular space
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005856 cytoskeleton
GO:0030027 lamellipodium
GO:0030175 filopodium
GO:0032982 myosin filament
GO:0044297 cell body
GO:0070062 extracellular exosome
GO:0071944 cell periphery
GO:0072562 blood microparticle

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:8v30, PDBe:8v30, PDBj:8v30
PDBsum8v30
PubMed38820162
UniProtP63267|ACTH_HUMAN Actin, gamma-enteric smooth muscle (Gene Name=ACTG2)

[Back to BioLiP]