Structure of PDB 8uzk Chain D

Receptor sequence
>8uzkD (length=486) Species: 1028307 (Klebsiella aerogenes KCTC 2190) [Search protein sequence]
AEQQLYIHGKFVAATSGKTFETINPATGEVLATVQAAGREDVDRAVKSAQ
QGQKVWAAMSAMARSRILRKAVDILRERNDELARLETLDTGKPLSETAAV
DIVTGADVLEYYAGLIPALEGSQIPLRDSSFVYTRREPLGVVAGIGAWNY
PIQIALWKSAPALAAGNAMIFKPSEVTPLTALKLAEIYREAGLPDGVFNV
LPGIGAETGQYLTEHPDIAKISFTGGVASGKKVMANSAASSLKEVTMELG
GKSPLIIAEDANLDLAADIAMMANFYSSGQVCTNGTRVFVPAKFKAEFEH
KILERVGRIRAGDLFADDTNFGPLVSFPHRQNVLRYIESGKSEGARLLCG
GDVLKGEGFDNGAWVAPTVFTDCTDDMTIVREEIFGPVMSILSYDDEAEV
IRRANATEYGLAAGVVTPDLNRAHRIIHQLEAGICWINSWGESPAEMPVG
GYKHSGIGRENGVMTLQSYTQVKSIQVEMGPFQSIF
3D structure
PDB8uzk Crystal Structure of Betaine aldehyde dehydrogenase (BetB) from Klebsiella aerogenes (NADP+ bound)
ChainD
Resolution1.9 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 1.2.1.8: betaine-aldehyde dehydrogenase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 NAP D I149 G150 A151 W152 K176 S178 E179 G209 G213 F227 G229 G230 S233 E252 C286 E387 F389 I145 G146 A147 W148 K172 S174 E175 G205 G209 F223 G225 G226 S229 E248 C282 E383 F385
BS02 NAP D L35 E85 R88 L89 L92 F319 L31 E81 R84 L85 L88 F315
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0008802 betaine-aldehyde dehydrogenase (NAD+) activity
GO:0016491 oxidoreductase activity
GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
GO:0046872 metal ion binding
Biological Process
GO:0019285 glycine betaine biosynthetic process from choline

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:8uzk, PDBe:8uzk, PDBj:8uzk
PDBsum8uzk
PubMed
UniProtA0A0H3FPU4

[Back to BioLiP]