Structure of PDB 8uw1 Chain D

Receptor sequence
>8uw1D (length=93) Species: 8355 (Xenopus laevis) [Search protein sequence]
RKESYAIYVYKVLKQVHPDTGISSKAMSIMNSFVNDVFERIAGEASRLAH
YNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSAK
3D structure
PDB8uw1 Cancer-associated DNA hypermethylation of Polycomb targets requires DNMT3A dual recognition of histone H2AK119 ubiquitination and the nucleosome acidic patch.
ChainD
Resolution2.88 Å
3D
structure
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Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna D R30 K31 R1 K2
External links
PDB RCSB:8uw1, PDBe:8uw1, PDBj:8uw1
PDBsum8uw1
PubMed39196936
UniProtP02281|H2B11_XENLA Histone H2B 1.1

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