Structure of PDB 8urk Chain D

Receptor sequence

>8urkD (length=244) Species: 95486 (Burkholderia cenocepacia) [Search protein sequence]

IELHNRDFLTDAAHLPDASIDLIVADPPYGLGKDYGNDSDKRSGDDFLAW
TREWLELAIPKLKPSGSMYIFCTWQYAPEIFSFLKTQLTMVNEIIWDRRV
PSMGGTTRRFTSVHDNIGFFAVSRAYYFDLDPVRIPYDADTKKARSRKLF
EGSKWLEMGYNPKDVWSVSRLHRQHAERVDHPTQKPLEIIERMVLASCPP
GGRVLDPFMGSGTTAVACARQGRDFVGYEINESYCAIAHERVNA

3D structure

PDB

8urk Burkholderia cenocepacia epigenetic regulator M.BceJIV simultaneously engages two DNA recognition sequences for methylation.

Chain

Resolution

2.11 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)
BS01	dna	D	R167 Y170 R178 R180 F183 K187 W188 N194 K196	R134 Y137 R145 R147 F150 K154 W155 N161 K163
BS02	dna	D	D59 P60 Y62 L64 Y68 D73 T106 W107 V133 S135 M136 G137 G138 T139 R142 S145 D148 R203 H205 R206 Q207 R211 T216 K218	D26 P27 Y29 L31 Y35 D40 T73 W74 V100 S102 M103 G104 G105 T106 R109 S112 D115 R170 H172 R173 Q174 R178 T183 K185
BS03	dna	D	R132 V133 P134 M136 G137 G138 T139 S202 H205 Q207 H208	R99 V100 P101 M103 G104 G105 T106 S169 H172 Q174 H175
BS04	SFG	D	R39 D40 D59 Y68 S72 H214 T216 K218 F241 M242 G243 S244 Y261 E262 I263 Y267	R6 D7 D26 Y35 S39 H181 T183 K185 F208 M209 G210 S211 Y228 E229 I230 Y234

External links

PDB	RCSB:8urk, PDBe:8urk, PDBj:8urk
PDBsum	8urk
PubMed	39244607
UniProt	A0A8I1DKW0

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