Structure of PDB 8upq Chain D

Receptor sequence
>8upqD (length=340) Species: 197 (Campylobacter jejuni) [Search protein sequence]
TVYYDKDCDLNLIKSKKVAIIGFGSQGHAHAMNLRDNGVNVTIGLREGSV
SAVKAKNAGFEVMSVSEASKIADVIMILAPDEIQADIFNVEIKPNLSEGK
AIAFAHGFNIHYGQIVVPKGVDVIMIAPKAPGHTVRNEFTLGGGTPCLIA
IHQDESKNAKNLALSYASAIGGGRTGIIETTFKAETETDLFGEQAVLCGG
LSALIQAGFETLVEAGYEPEMAYFECLHEMKLIVDLIYQGGIADMRYSIS
NTAEYGDYITGPKIITEETKKAMKGVLKDIQNGVFAKDFILERRAGFARM
HAERKNMNDSLIEKTGRNLRAMMPWISAKKLVDADKNYKH
3D structure
PDB8upq Mapping of the Reaction Trajectory catalyzed by Class I Ketol-Acid Reductoisomerase
ChainD
Resolution2.45 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 1.1.1.86: ketol-acid reductoisomerase (NADP(+)).
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 XAI D D192 E196 D189 E193
BS02 MG D D192 E196 D189 E193
BS03 XAI D E232 S253 A256 E229 S250 A253
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0004455 ketol-acid reductoisomerase activity
GO:0016491 oxidoreductase activity
GO:0046872 metal ion binding
GO:0050661 NADP binding
Biological Process
GO:0008652 amino acid biosynthetic process
GO:0009082 branched-chain amino acid biosynthetic process
GO:0009097 isoleucine biosynthetic process
GO:0009099 L-valine biosynthetic process
Cellular Component
GO:0005829 cytosol

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:8upq, PDBe:8upq, PDBj:8upq
PDBsum8upq
PubMed
UniProtQ9PHN5|ILVC_CAMJE Ketol-acid reductoisomerase (NADP(+)) (Gene Name=ilvC)

[Back to BioLiP]