Structure of PDB 8unf Chain D

Receptor sequence
>8unfD (length=319) Species: 10665 (Tequatrovirus T4) [Search protein sequence]
MITVNEKEHILEQKYRPSTIDECILPAFDKETFKSITSKGKIPHIILHSP
SPGTGKTTVAKALCHDVNADMMFVNGSDCKIDFVRGPLTNFASAASFDGR
QKVIVIDEFDRSGLAESQRHLRSFMEAYSSNCSIIITANNIDGIIKPLQS
RCRVITFGQPTDEDKIEMMKQMIRRLTEICKHEGIAIADMKVVAALVKKN
FPDFRKTIGELDSYSSKGVLDAGILSLVTNDRGAIDDVLESLKNKDVKQL
RALAPKYAADYSWFVGKLAEEIYSRVTPQSIIRMYEIVGENNQYHGIAAN
TELHLAYLFIQLACEMQWK
3D structure
PDB8unf Autoinhibition of a clamp-loader ATPase revealed by deep mutagenesis and cryo-EM
ChainD
Resolution3.15 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.4.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna D K80 I81 R85 R111 G113 K80 I81 R85 R111 G113
BS02 08T D E12 R16 P17 I24 P52 G53 T54 G55 K56 T57 T58 E108 N139 F204 R205 E12 R16 P17 I24 P52 G53 T54 G55 K56 T57 T58 E108 N139 F204 R205
BS03 MG D T57 D107 E108 T57 D107 E108
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003689 DNA clamp loader activity
GO:0005524 ATP binding
GO:0016787 hydrolase activity
GO:0016887 ATP hydrolysis activity
Biological Process
GO:0006260 DNA replication
GO:0006261 DNA-templated DNA replication
GO:0006281 DNA repair
GO:0039686 bidirectional double-stranded viral DNA replication
GO:0039693 viral DNA genome replication
Cellular Component
GO:0005663 DNA replication factor C complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8unf, PDBe:8unf, PDBj:8unf
PDBsum8unf
PubMed38177685
UniProtP04526|LOADL_BPT4 Sliding-clamp-loader large subunit (Gene Name=44)

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