Structure of PDB 8u72 Chain D

Receptor sequence

>8u72D (length=411) Species: 1393122 (Thermoflavifilum thermophilum) [Search protein sequence]

NKIFISHATPEDDDFTRWLSLKLIGLGYEVWCDILFWSTIEKEIRENTCK
FLIVSSTAGNKREGVLKELAVATKVKKHLQDDMFIIPLAIDENLSYDDIN
IEIVRLNAIDFKKSWAKGLQDLLDAFEKQNVPKKPPDHSKSNLLYQQIFL
HDKQAIEKEETYDSNWFPIISFPNELRFHRYDWRLPKQFDVRTLAFPAIR
YKEYLCTFAWEYDFIHQLPKTETYNGQESIRISTSDILSGRYDTDFIRNY
ECQRLIVQLINKAFELRMKDKNVREYQMSKTFAYWIEKGKLEKDKFEKIK
LVGKQKNKYWHFGISAAGKLYPSPVLMVSSHIIFTMDGINLIKSKSIQHS
SRRKQGKNWWNDKWREKLLAFIRFLSDDQNAIYLNVGSEEKILISNKPLK
FFGKMSYVTPS

3D structure

PDB

8u72 Nucleic acid mediated activation of prokaryotic Argonaute immune system

Chain

Resolution

3.15 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	D	K211 E212 E260 R263 M287 S288 K289 H340 K354 H358 R362	K202 E203 E251 R254 M278 S279 K280 H331 K345 H349 R353
BS02	dna	D	R201 R263 V266 H358	R192 R254 V257 H349

External links

PDB	RCSB:8u72, PDBe:8u72, PDBj:8u72
PDBsum	8u72
PubMed	38844755
UniProt	A0A1I7NFG5

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