Structure of PDB 8u43 Chain D

Receptor sequence
>8u43D (length=556) Species: 10116 (Rattus norvegicus) [Search protein sequence]
LKQFVNASYTDSYYKGQTALHIAIERRNMTLVTLLVENGADVQAAANGDF
FKKTKGRPGFYFGELPLSLAACTNQLAIVKFLLQNSWQPADISARDSVGN
TVLHALVEVADNTVDNTKFVTSMYNEILILGAKLHPTLKLEEITNRKGLT
PLALAASSGKIGVLAYILQREIHEPECRHLSRKFTEWAYGPVHSSLYDLS
CIDTCEKNSVLEVIAYSSSETPNRHDMLLVEPLNRLLQDKWDRFVKRIFY
FNFFVYCLYMIIFTAAAYYRPVEGLPPYKLKNTVGDYFRVTGEILSVSGG
VYFFFRGIQYFLQRRPSLKSLFVDSYSEILFFVQSLFMLVSVVLYFSQRK
EYVASMVFSLAMGWTNMLYYTRGFQQMGIYAVMIEKMILRDLCRFMFVYL
VFLFGFSTAVVTLIEDGKYNSLYSTCLELFKFTIGMGDLEFTENYDFKAV
FIILLLAYVILTYILLLNMLIALMGETVNKIAQESKNIWKLQRAITILDT
EKSFLKCMRKAFRSGKLLQVGFTPDGKDDYRWCFRVDEVNWTTWNTNVGI
INEDPG
3D structure
PDB8u43 Structural basis of TRPV1 modulation by endogenous bioactive lipids.
ChainD
Resolution2.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 V5H D H410 V508 D509 Y511 S512 T550 L553 R557 E570 K571 I696 H225 V323 D324 Y326 S327 T365 L368 R372 E385 K386 I488
Gene Ontology
Molecular Function
GO:0005216 monoatomic ion channel activity
Biological Process
GO:0006811 monoatomic ion transport
GO:0055085 transmembrane transport
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8u43, PDBe:8u43, PDBj:8u43
PDBsum8u43
PubMed38698206
UniProtO35433|TRPV1_RAT Transient receptor potential cation channel subfamily V member 1 (Gene Name=Trpv1)

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