Structure of PDB 8u2z Chain D

Receptor sequence
>8u2zD (length=510) Species: 10116 (Rattus norvegicus) [Search protein sequence]
GQTALHIAIERRNMTLVTLLVENGADVQAAANGDFFPGFYFGELPLSLAA
CTNQLAIVKFLLQNSWQPADISARDSVGNTVLHALVEVADNTVDNTKFVT
SMYNEILILGAKLHPTLKLEEITNRKGLTPLALAASSGKIGVLAYILQRE
IHEPECRHLSRKFTEWAYGPVHSSLYDLSCIDTCEKNSVLEVIAYSSSET
PNRHDMLLVEPLNRLLQDKWDRFVKRIFYFNFFVYCLYMIIFTAAAYYRP
VEGLPPYKLKNTVGDYFRVTGEILSVSGGVYFFFRGIQYFLQRRPSLKSL
FVDSYSEILFFVQSLFMLVSVVLYFSQRKEYVASMVFSLAMGWTNMLYYT
RGFQQMGIYAVMIEKMILRDLCRFMFVYLVFLFGFSTAVVTLIEDGKYNS
LYSTCLELFKFTIGMGDLEFTENYDFKAVFIILLLAYVILTYILLLNMLI
ALMGETVNKIAQELQRAITILDTEKSAFRSGKLLQVGFTPDGKDDYRWCF
RVDEVNWTTW
3D structure
PDB8u2z Structural basis of TRPV1 modulation by endogenous bioactive lipids.
ChainD
Resolution3.6 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 PIO D I661 A665 L669 I432 A436 L440
BS02 CLR D T641 V667 Y671 T412 V438 Y442
BS03 PIO D Y511 S512 L515 F543 M547 T550 N551 Y554 I569 Y305 S306 L309 F337 M341 T344 N345 Y348 I363
BS04 CLR D L577 F580 M677 L371 F374 M448
Gene Ontology
Molecular Function
GO:0005216 monoatomic ion channel activity
Biological Process
GO:0006811 monoatomic ion transport
GO:0055085 transmembrane transport
Cellular Component
GO:0016020 membrane

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:8u2z, PDBe:8u2z, PDBj:8u2z
PDBsum8u2z
PubMed38698206
UniProtO35433|TRPV1_RAT Transient receptor potential cation channel subfamily V member 1 (Gene Name=Trpv1)

[Back to BioLiP]