Structure of PDB 8u17 Chain D

Receptor sequence
>8u17D (length=349) Species: 9606 (Homo sapiens) [Search protein sequence]
TLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTF
AVLAYSQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRT
QSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPSYKWWQKYQK
RKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPID
FSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQET
EITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHS
WFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPD
3D structure
PDB8u17 Structural and biophysical comparisons of the pomalidomide- and CC-220-induced interactions of SALL4 with cereblon.
ChainD
Resolution3.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN D C323 C326 C391 C394 C244 C247 C312 C315
BS02 Y70 D N351 P352 H353 H378 W380 W386 W400 N272 P273 H274 H299 W301 W307 W321
External links
PDB RCSB:8u17, PDBe:8u17, PDBj:8u17
PDBsum8u17
PubMed38086859
UniProtQ96SW2|CRBN_HUMAN Protein cereblon (Gene Name=CRBN)

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