Structure of PDB 8ttc Chain D

Receptor sequence

>8ttcD (length=299) Species: 10090 (Mus musculus) [Search protein sequence]

QSLVGRFIHLLRSDDPDQQYLILNTARKHFGAGGNQRIRFTLPPLVFAAY
QLAFRYKENSQMDDKWEKKCQKIFSFAHQTISALIKAELAELPLRLFLQG
ALAAGEIGFENHETVAYEFMSQAFSLYEDEISDSKAQLAAITLIIGTFER
MKCFSEENHEPLRTQCALAASKLLKKPDQGRAVSTCAHLFWSGRNTDKNG
EELHGGKRVMECLKKALKIANQCMDPSLQVQLFIEILNRYIYFYEKENDA
VTIQVLNQLIQKIREDLPNLESSEETEQINKHFHNTLEHLRSRRESPES

3D structure

PDB

8ttc Structural basis for coupling of the WASH subunit FAM21 with the endosomal SNX27-Retromer complex.

Chain

Resolution

3.01 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	peptide	D	D504 Y543 K555 K556 K559	D17 Y56 K68 K69 K72

External links

PDB	RCSB:8ttc, PDBe:8ttc, PDBj:8ttc
PDBsum	8ttc
PubMed	39116126
UniProt	Q9EQH3\|VPS35_MOUSE Vacuolar protein sorting-associated protein 35 (Gene Name=Vps35)

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