Structure of PDB 8tcc Chain D

Receptor sequence
>8tccD (length=244) Species: 28450 (Burkholderia pseudomallei) [Search protein sequence]
QMPIQRVGVRAVRHPLTVRTAEGETQATVGTWNLDVHLPADQKGTHMSRF
VALLEERGGPLTADAFRTMLATMLEKLEARAGRIEVSFPYFVNKTAPVSG
VRSLLDYEVTLTGDVRDLTRVFAKVLVPVTSLCPCSKKIQYGAHNQRSHV
TIDAELAADVPVEDLIRIAEEEASCELWGLLKRPDEKFVTERAYENPKFV
EDLVRDVARRLDADERIVAYVLEAENFESIHNHSAYALIERDKR
3D structure
PDB8tcc Combatting melioidosis with chemical synthetic lethality
ChainD
Resolution3.1 Å
3D
structure
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Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 ZS9 D C154 X156 H166 F221 I252 H253 C133 X135 H144 F199 I230 H231
Gene Ontology
Molecular Function
GO:0003933 GTP cyclohydrolase activity
GO:0003934 GTP cyclohydrolase I activity
GO:0016787 hydrolase activity
GO:0046872 metal ion binding
Biological Process
GO:0046654 tetrahydrofolate biosynthetic process

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Molecular Function

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Biological Process
External links
PDB RCSB:8tcc, PDBe:8tcc, PDBj:8tcc
PDBsum8tcc
PubMed
UniProtA0A069BB45

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