Structure of PDB 8t59 Chain D

Receptor sequence
>8t59D (length=219) Species: 32630 (synthetic construct) [Search protein sequence]
DVVMTQSPLSLPVTPGEPASISCRSSRSLLTSKGITSLYWYLQKPGQSPQ
LLIYRMSNLASGIPDRFSGSGSGTDFTLKISRVEAEDVGVYYCAQFLVYP
YTFGPGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAK
VQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACE
VTHQGLSSPVTKSFNRGEC
3D structure
PDB8t59 Rapid affinity optimization of an anti-TREM2 clinical lead antibody by cross-lineage immune repertoire mining
ChainD
Resolution2.0 Å
3D
structure
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Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide D T31 S32 S37 Y39 R55 F96 L97 Y101 T31 S32 S37 Y39 R55 F96 L97 Y101
BS02 ZN D E84 E86 E84 E86
BS03 ZN D N142 N143 N142 N143
BS04 ZN D D190 H194 D190 H194
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