Structure of PDB 8suv Chain D

Receptor sequence
>8suvD (length=128) Species: 9606 (Homo sapiens) [Search protein sequence]
SPSAQELKEQGNRLFVGRKYPEAAACYGRAITRNPLVAVYYTNRALCYLK
MQQHEQALADCRRALELDGQSVKAHFFLGQCQLEMESYDEAIANLQRAYS
LAKEQRLNFGDDIPSALRIAKKKRWNSI
3D structure
PDB8suv Interaction with the membrane-anchored protein CHIC2 constrains the ubiquitin ligase activity of CHIP
ChainD
Resolution1.63 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.2.27: RING-type E3 ubiquitin transferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide D K30 N34 F37 Y49 N65 L68 K95 F98 F99 Q102 N130 F131 G132 D134 I135 K8 N12 F15 Y27 N43 L46 K73 F76 F77 Q80 N108 F109 G110 D112 I113
External links
PDB RCSB:8suv, PDBe:8suv, PDBj:8suv
PDBsum8suv
PubMed
UniProtQ9UNE7|CHIP_HUMAN E3 ubiquitin-protein ligase CHIP (Gene Name=STUB1)

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