Structure of PDB 8srp Chain D

Receptor sequence
>8srpD (length=86) Species: 10090 (Mus musculus) [Search protein sequence]
NMDYFKYHNMRPPFTYATLIRWAILEAPERQRTLNEIYHWFTRMFAYFRN
HPATWKNAIRHNLSLHKCFVRVESEKGAVWTVDEFE
3D structure
PDB8srp FoxP3 forms Ladder-like multimer to bridge TTTG repeats
ChainD
Resolution3.7 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 dna D R337 T341 Y342 R11 T15 Y16
BS02 dna D L360 R386 H387 S390 R397 W406 L34 R60 H61 S64 R71 W80
Gene Ontology
Molecular Function
GO:0003700 DNA-binding transcription factor activity
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0006355 regulation of DNA-templated transcription

View graph for
Molecular Function

View graph for
Biological Process
External links
PDB RCSB:8srp, PDBe:8srp, PDBj:8srp
PDBsum8srp
PubMed38030726
UniProtQ99JB6|FOXP3_MOUSE Forkhead box protein P3 (Gene Name=Foxp3)

[Back to BioLiP]