Structure of PDB 8soj Chain D

Receptor sequence
>8sojD (length=490) Species: 9606 (Homo sapiens) [Search protein sequence]
TLLKLCDVQPMQYFDLTCQLLGKAEVDGASFLLKVWDGTRTPFPSWRVLI
QDLVLEGDLSHIHRLQNLTIDILVYDNHVHVARSLKVGSFLRIYSLHTKL
QSMNSENQTMLSLEFHLHGGTSYGRGIRVLPESNSDVDQLKKDLESANLT
ANQHSDVICQSEPDDSFPSSGSESDLVSLYEVERCQQLSATILTDHQYLE
RTPLCAILKQKAPQQYRIRAKLRSYKPRRLFQSVKLHCPKCHLLQEVPHE
GDLDIIFQDGATKTPDVKLQNTSLYDSKIWTTKNQKGRKVAVHFVKNNGI
LPLSNECLLLIEGGTLSEICKLSNKFNSVIPVRSGHEDLELLDLSAPFLI
QGTIHHYGCKQCSSLRSIQNLNSLVDKTSWIPSSVAEALGIVPLQYVFVM
TFTLDDGTGVLEAYLMDSDKFFQIPASEVLMDDDLQKSVDMIMDMFCPPG
IKIDAYPWLECFIKSYNVTNGTDNQICYQIFDTTVAEDVI
3D structure
PDB8soj Structural basis of CST-Pol alpha /Primase recruitment and regulation by POT1 at telomeres.
ChainD
Resolution3.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 ZN D C382 C503 C238 C359
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0043047 single-stranded telomeric DNA binding
Biological Process
GO:0000723 telomere maintenance
Cellular Component
GO:0000781 chromosome, telomeric region

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:8soj, PDBe:8soj, PDBj:8soj
PDBsum8soj
PubMed37215005
UniProtQ9NUX5|POTE1_HUMAN Protection of telomeres protein 1 (Gene Name=POT1)

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