Structure of PDB 8sli Chain D

Receptor sequence
>8sliD (length=894) Species: 10116 (Rattus norvegicus) [Search protein sequence]
CKGEVNFKRSKFVKVPSNVAPSMLFELLLTEWHLPAPNLVVSLVGEERLF
AMKSWLRDVLRKGLVKAAQSTGAWILTSAGLARHVGQAVRDHSLAVRVVA
IGMASLDRILHRQLLDGTPIHYPADLCPLDSNLSHFILVAELQLSLEKHI
SQQRTGSSIQIPVLCLLVNGDPSTLERMSRAVEQAAPWLILGGIADVLAA
LVGQPHLLVPQVTEKQFREKFPSECFSWEAIVHWTELLQNIAAHPHLLTV
YDFDLDTVILKALVKACKSHSRDAQDYLDELKLAVAWDRVDIAKSEIFNG
DVEWKSCDLEEVMTDALVSNKPDFVRLFVDSGADMAEFLTYGRLQQLYHS
VSPKSLLFELLERKHEEGRLPAFSLHEVSRVLKDFLHDACRGFYQWLPDL
SRKSEDPWRDLFLWAVLQNRYEMATYFWAMGREGVAAALAACKIIKEMSH
LEKEAEVARTMREAKYEQLALDLFSECYSNSEDRAFALLVRRNHSWSRTT
CLHLATEADAKAFFAHDGVQAFLTKIWWGDMATILRLLGAFTCPALIYTN
LISFSAAFLLTRWRKFWGAPVTVFLGNVVMYFAFLFLFSYVLLVDFRPPP
QGPSGSEVTLYFWVFTLVLEEIRQGFFTDTRLVKKFTLYVEDNWNKCDMV
AIFLFIVGVTCRMVPSVFEAGRTVLAIDFMVFTLRLIHIFAIHKQLGPKI
IIVERMMKDVFFFLFFLSVWLVAYGVTTQALLHLEWIFRRVLYRPYLQIF
GQIPLDEIDEARVLYANWLVILLLVTFLLVTNVLLMNLLIAMFSYTFQVV
QGNADMFWKFQRYHLIVEYHGRPALAPPFILLSHLSLVLKQVFRPDPVDQ
KIITWETVQKENFLSTMEKRRRDSEEEVLRKTAHRVDLIAKYIG
3D structure
PDB8sli Structural dynamics at cytosolic interprotomer interfaces control gating of a mammalian TRPM5 channel.
ChainD
Resolution4.9 Å
3D
structure
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Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 CA D Q225 D350 E354 Q160 D276 E280
BS02 CA D Q784 N807 D810 Q624 N645 D648
External links