Structure of PDB 8sl7 Chain D

Receptor sequence
>8sl7D (length=544) Species: 2584625 (Butyricicoccus sp. BIOML-A1) [Search protein sequence]
KQYPLNVPAPHHFTYAVRDLPEVTVEQRERALQATHYNEFAFPSGMLTVD
MLSDSGTTAMTNHQWASLFLGDEAYGRNTGYYVLLDTFRDIFERGGEKNW
KKIIDLVRTDCRDVEKMMDEVYLCEYEGGLFNGGAAQMERPNAFIIQQGR
AAESVLMEIVRNILAKRHPGKKFTIPSNGHFDTTEGNIKQMGSIPRNLYN
KTLLWETPEGGRYEKNPFKGNMDIEKLEQLIQGVGPENVPLIFTCITNNP
VCGQAVSMGNLKEINRVAHKYNIPLVFDTARWAENAYFIKMNEEGYADKS
IAEIATEMFSYCDAFTMSAKKDGHANMGGMLAFRDKGLFWKNFSDFNEDG
TVKTDVGVLLKVKQISCYGNDSYGGMSGRDIMALAVGLYESCDFNYMNER
VAQCNYLAEGFYDAGVKGVVLPAGGHAVYINMDEFFDGKRGHDTFAGEGF
SLELIRRYGIRVSELGDYSMEYDLKTPEQQAEVCNVVRFAIDRSRLTKEH
LDYVIAAVKALYEDRENIPNMRIVWGHNLPMRHFHAFLEPYANE
3D structure
PDB8sl7 Mechanism-based inhibition of gut microbial tryptophanases reduces serum indoxyl sulfate.
ChainD
Resolution2.07 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 4.1.99.1: tryptophanase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 BY3 D F42 S55 S57 Q150 G151 R152 F183 D184 T185 N251 D280 R283 S320 K323 S465 L467 R490 H535 F536 F40 S53 S55 Q148 G149 R150 F181 D182 T183 N249 D278 R281 S318 K321 S463 L465 R488 H533 F534
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0016829 lyase activity
Biological Process
GO:0006520 amino acid metabolic process

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Molecular Function
View graph for
Biological Process
External links
PDB RCSB:8sl7, PDBe:8sl7, PDBj:8sl7
PDBsum8sl7
PubMed37633277
UniProtA0A845MXR5

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