Structure of PDB 8s3x Chain D

Receptor sequence
>8s3xD (length=263) Species: 9606 (Homo sapiens) [Search protein sequence]
LIHGEVLGKGFFGQAIKVTVMVMKELIDEETQKTFLTEVKVMRSLDHPNV
LKFIGVLYKDKKLNLLTEYIEGGTLKDFLRSMFPWQQKVRFAKGIASGMA
YLHSMCIIHRDLNSHNCLIKLDKTVVVADFGLSRLIRYTVVGNPYWMAPE
MLNGKSYDETVDIFSFGIVLCEIIGQVYADPDCLPRTLDFGLNVKLFWEK
FVPTDCPPAFFPLAAICCRLEPESRPAFSKLEDSFEALSLYLLGIPLPAE
LEELDHTVSMQYG
3D structure
PDB8s3x Macromolecular structure determination using X-rays, neutrons and electrons: recent developments in Phenix
ChainD
Resolution2.59 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 2.7.11.1: non-specific serine/threonine protein kinase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 A1H41 D F342 A345 Y407 I408 D469 F12 A15 Y69 I70 D129
Gene Ontology
Molecular Function
GO:0004672 protein kinase activity
GO:0005524 ATP binding
Biological Process
GO:0006468 protein phosphorylation

View graph for
Molecular Function

View graph for
Biological Process
External links
PDB RCSB:8s3x, PDBe:8s3x, PDBj:8s3x
PDBsum8s3x
PubMed38669909
UniProtP53671|LIMK2_HUMAN LIM domain kinase 2 (Gene Name=LIMK2)

[Back to BioLiP]