Structure of PDB 8rhg Chain D

Receptor sequence

>8rhgD (length=330) Species: 9606 (Homo sapiens) [Search protein sequence]

QLLRIDDHDFSMRPGFGGPAIPVGVDVQVESLDSISEVDMDFTMTLYLRH
YWKDERLSFPSTNNLSMTFDGRLVKKIWVPDMFFVHSKRSFIHDTTTDNV
MLRVQPDGKVLYSLRVTVTAMCNMDFSRFPLDTQTCSLEIESYAYTEDDL
MLYWKKGNDSLKTDERISLSQFLIQEFHTTTKLAFYSSTGWYNRLYINFT
LRRHIFFFLLQTYFPATLMVMLSWVSFWIDRRAVPARVPLGITTVLTMST
IITGVNASMPRVSYIKAVDIYLWVSFVFVFLSVLEYAAVNYLTTVQERKE
QDTHAIDKYSRIIFPAAYILFNLIYWSIFS

3D structure

PDB

8rhg Divergent mechanisms of steroid inhibition in the human rho1 GABAA receptor

Chain

Resolution

3.01 Å

3D
structure

[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	ABU	D	R125 S189	R49 S113
BS02	ABU	D	Y219 T265 Y268	Y143 T189 Y192

External links

PDB	RCSB:8rhg, PDBe:8rhg, PDBj:8rhg
PDBsum	8rhg
PubMed
UniProt	P24046\|GBRR1_HUMAN Gamma-aminobutyric acid receptor subunit rho-1 (Gene Name=GABRR1)

[Back to BioLiP]