Structure of PDB 8rd7 Chain D

Receptor sequence
>8rd7D (length=74) Species: 9606 (Homo sapiens) [Search protein sequence]
NWRWFDDRSGRWCSYSASNNSTIDSAWKSGETSVRFTAGRRRYTVQFTTM
VQVNEETGNRRPVMLTLLRVPRLN
3D structure
PDB8rd7 A ligand discovery toolbox for the WWE domain family of human E3 ligases
ChainD
Resolution1.31 Å
3D
structure
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Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 AR6 D W1619 A1653 R1656 Y1658 Q1667 N1669 T1672 N1674 R1676 W4 A38 R41 Y43 Q52 N54 T57 N59 R61
External links
PDB RCSB:8rd7, PDBe:8rd7, PDBj:8rd7
PDBsum8rd7
PubMed39048679
UniProtQ7Z6Z7|HUWE1_HUMAN E3 ubiquitin-protein ligase HUWE1 (Gene Name=HUWE1)

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