Structure of PDB 8r3p Chain D

Receptor sequence
>8r3pD (length=668) Species: 1352 (Enterococcus faecium) [Search protein sequence]
MFDKIDQLGVNTIRTLSIEAVQKANSGHPGLPMGAAPMAYALWTKHLKVN
PTTSKNWADRDRFVLSAGHGSAMLYSLLHLAGYQVTIDDLKQFRQWDSKT
PGHPEVHHTDGVEATTGPLGQGIAMAVGMAMAEAHLAATYNKENFNVMDH
YTYAICGDGDLMEGVSQEASSMAGHMKLGKLIVLYDSNDISLDGPTSKAF
TENVGARYEAYGWQHILVKDGNDLEAISKAIEEAKAETDKPTLIEVKTVI
GYGAPKEGTSAVHGAPLGEDGIKMAKEVYGWEYPDFTVPEEVAARFHQTM
IEEGQKAEDAWNEMFANYKKAYPELAQQFEDAFDGKLPENWDAELPTYEV
GSSQASRVSSKEVIQELSKAIPSFWGGSADLSGSNNTMVAADKDFTPEHY
EGRNIWFGVREFAMASAMNGIQLHGGTRIYGGTFFVFVDYLRPAVRLAAI
QHTPVVYVLTHDSVAVGEDGPTHEPIEQLASVRCMPGVQVIRPADGNETR
AAWKVAMETTDAPTILVLSRQNLPVLPSTKEVADEMVKKGAYVLSPSQGE
TPEGILIATGSEVDLAVKAQKELAEKGKDVSVVSMPSFDLFEKQSSEYKE
SVLPKSVKKRVAIEAAASFGWERYVGTEGATITIDHFGASAPGTKILEEF
GFTVENVVNTYNQLSENL
3D structure
PDB8r3p Are Transketolases relevant Targets fighting Human Pathogens? A comparative Biochemical, Bioinformatic and Structural Study
ChainD
Resolution2.9 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 2.2.1.1: transketolase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 TPP D F437 Y440 H473 F437 Y440 H473
BS02 TPP D H69 L119 G157 D158 G159 N188 I190 L192 I250 H263 H69 L119 G157 D158 G159 N188 I190 L192 I250 H263
BS03 MG D D158 N188 D158 N188
Gene Ontology
Molecular Function
GO:0004802 transketolase activity
GO:0016740 transferase activity
GO:0046872 metal ion binding
Biological Process
GO:0006098 pentose-phosphate shunt
Cellular Component
GO:0005829 cytosol

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:8r3p, PDBe:8r3p, PDBj:8r3p
PDBsum8r3p
PubMed
UniProtA0A133CKH8

[Back to BioLiP]