Structure of PDB 8r02 Chain D

Receptor sequence
>8r02D (length=293) Species: 9606 (Homo sapiens) [Search protein sequence]
QSLVGRFIHLLRSEDPDQQYLILNTARKHFGAGGNQRIRFTLPPLVFAAY
QLAFRYKENSKVDDKWEKKCQKIFSFAHQTISALIKAELAELPLRLFLQG
ALAAGEIGFENHETVAYEFMSQAFSLYEDEISDSKAQLAAITLIIGTFER
MKCFSEENHEPLRTQCALAASKLLKKPDQGRAVSTCAHLFWSGRNTDKNG
EELHGGKRVMECLKKALKIANQCMDPSLQVQLFIEILNRYIYFYEKENDA
VTIQVLNQLIQKIREDLPNLESSEETEQINKHFHNTLEHLRLR
3D structure
PDB8r02 Stabilization of the retromer complex: Analysis of novel binding sites of bis-1,3-phenyl guanylhydrazone 2a to the VPS29/VPS35 interface.
ChainD
Resolution2.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 XFZ D E722 R726 E235 R239
Gene Ontology
Biological Process
GO:0015031 protein transport
GO:0042147 retrograde transport, endosome to Golgi
Cellular Component
GO:0030906 retromer, cargo-selective complex

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Biological Process
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Cellular Component
External links
PDB RCSB:8r02, PDBe:8r02, PDBj:8r02
PDBsum8r02
PubMed38487369
UniProtQ96QK1|VPS35_HUMAN Vacuolar protein sorting-associated protein 35 (Gene Name=VPS35)

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