Structure of PDB 8qmz Chain D

Receptor sequence
>8qmzD (length=320) Species: 9606 (Homo sapiens) [Search protein sequence]
LPTSCNPSDMSHGYVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQ
IPALAQAGYRVLAMDMKGYGESSAPPEIEEYCMEVLCKEMVTFLDKLGLS
QAVFIGHDWGGMLVWYMALFYPERVRAVASLNTPFIPANPNMSPLESIKA
NPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSMHKVCEAGG
LFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWAC
KSLGRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQ
MDKPTEVNQILIKWLDSDAR
3D structure
PDB8qmz Photosensitization enables Pauson-Khand-type reactions with nitrenes.
ChainD
Resolution1.47 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.3.76: lipid-phosphate phosphatase.
3.3.2.10: soluble epoxide hydrolase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 W6O D D335 W336 Y383 Q384 M419 Y466 V498 L499 H524 D108 W109 Y156 Q157 M192 Y239 V271 L272 H297
Gene Ontology
Molecular Function
GO:0003824 catalytic activity

View graph for
Molecular Function
External links
PDB RCSB:8qmz, PDBe:8qmz, PDBj:8qmz
PDBsum8qmz
PubMed38301027
UniProtP34913|HYES_HUMAN Bifunctional epoxide hydrolase 2 (Gene Name=EPHX2)

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