Structure of PDB 8qd3 Chain D

Receptor sequence
>8qd3D (length=398) Species: 746128 (Aspergillus fumigatus) [Search protein sequence]
RWILGDKFDTVFPHKGSLKVLWESRWKFACSKSVYPFHDGSIEDFEPIFN
HLISKNINDAASDEYTQAFLPTASALEEKAAQALQAGKHEEASNLLCRAA
VVYRISRFPYVDITKPNSIKRVAFERQKQAYLKATSLWTQPIREVTVPHT
YRTGNDGAHIPIYIRTPAGADQSNPVPIVLIMTGLDGYRPDNSQRTHEIL
ARGWAAVVAEIPGTADCPADPADPASPDRLWDSVLSYLDQRPELNTAKMV
VWGLSAGGYYAIRAAHTHRDRLLGAIAHGPGCHYYLDPEWLAKVNDHEYP
FEITAAWATKHGYKTVEEFVAGAQKKFSLVETGIVDQPSCRLLLLNGVDD
GVVPIEDCLVLFEHGSPKEGRFYKGLPHMGYPNSLPVSYEWLEQVLAS
3D structure
PDB8qd3 Polyketide trimming shapes dihydroxynaphthalene-melanin and anthraquinone pigments
ChainD
Resolution1.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.7.1.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 QW8 D Y37 G186 D188 G189 S257 H380 Y383 Y35 G184 D186 G187 S255 H378 Y381
BS02 FLV D Y37 G186 D188 G189 L256 S257 H380 Y383 Y35 G184 D186 G187 L254 S255 H378 Y381
BS03 FLV D Y37 G186 D188 G189 S257 H380 M381 Y383 Y35 G184 D186 G187 S255 H378 M379 Y381
Gene Ontology
Molecular Function
GO:0003674 molecular_function
GO:0016787 hydrolase activity
Biological Process
GO:0030640 polyketide catabolic process
GO:0042438 melanin biosynthetic process
GO:0046148 pigment biosynthetic process
Cellular Component
GO:0005575 cellular_component
GO:0005768 endosome

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8qd3, PDBe:8qd3, PDBj:8qd3
PDBsum8qd3
PubMed38491909
UniProtQ4WZB3|AYG1_ASPFU Heptaketide hydrolyase ayg1 (Gene Name=ayg1)

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