Structure of PDB 8pj1 Chain D

Receptor sequence

>8pj1D (length=177) Species: 9606 (Homo sapiens) [Search protein sequence]

PVARSWVCRKTYVTPRRPFEKSRLDQELKLIGEYGLRNKREVWRVKFTLA
KIRKAARELLTLDEKDPRRLFEGNALLRRLVRIGVLDEGKMKLDYILGLK
IEDFLERRLQTQVFKLGLAKSIHHARVLIRQRHIRVRKQVVNIPSFIVRL
DSQKHIDFSLRSPYGGGRPGRVKRKNA

3D structure

PDB

8pj1 Structural basis for translational control by the human 48S initiation complex from codon scanning toward subunit joining

Chain

Resolution

3.4 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	D	P2 V3 A4 R5 W7 V8 C9 R10 K11 T12 Y13 T15 P16 R17 R18 P19 F20 K22 R38 N39 K40 R41 R45 F72 E73 R79 R80 R83 K121 H125 R127 R131 Q132 R133 H134 Q140 V142 N143 I144 P145 S146 F147 I148 R150 S153 P164 R169 P170 G171 R172 V173 K174 K176 N177	P1 V2 A3 R4 W6 V7 C8 R9 K10 T11 Y12 T14 P15 R16 R17 P18 F19 K21 R37 N38 K39 R40 R44 F71 E72 R78 R79 R82 K120 H124 R126 R130 Q131 R132 H133 Q139 V141 N142 I143 P144 S145 F146 I147 R149 S152 P163 R168 P169 G170 R171 V172 K173 K175 N176

External links

PDB	RCSB:8pj1, PDBe:8pj1, PDBj:8pj1
PDBsum	8pj1
PubMed
UniProt	P46781\|RS9_HUMAN Small ribosomal subunit protein uS4 (Gene Name=RPS9)

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