Structure of PDB 8pep Chain D

Receptor sequence
>8pepD (length=94) Species: 8355 (Xenopus laevis) [Search protein sequence]
TRKESYAIYVYKVLKQVHPDTGISSKAMSIMNSFVNDVFERIAGEASRLA
HYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSAK
3D structure
PDB8pep Multivalency of nucleosome recognition by LEDGF.
ChainD
Resolution3.33 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 dna D Y39 I51 R83 T85 Y11 I23 R55 T57
BS02 dna D R30 I36 Y37 R2 I8 Y9
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0030527 structural constituent of chromatin
GO:0046982 protein heterodimerization activity
Cellular Component
GO:0000786 nucleosome
GO:0005634 nucleus
GO:0005694 chromosome

View graph for
Molecular Function

View graph for
Cellular Component
External links
PDB RCSB:8pep, PDBe:8pep, PDBj:8pep
PDBsum8pep
PubMed37615563
UniProtP02281|H2B11_XENLA Histone H2B 1.1

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