Structure of PDB 8p0f Chain D

Receptor sequence
>8p0fD (length=146) Species: 9606 (Homo sapiens) [Search protein sequence]
VLRSVNSREPSQVIFCNRSPRVVLPVWLNFDGEPQPYPTLPPGTGRRIHS
YRGHLWLFRDAGTHDGLLVNQTELFVPSLNVDGQPIFANITLPVYTLKER
CLQVVRSLVKPENYRRLDIVRSLYEDLEDHPNVQKDLERLTQERIA
3D structure
PDB8p0f Drugit: Crowd-sourcing molecular design of non-peptidic VHL binders
ChainD
Resolution1.98 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 WBN D F76 W88 F91 Y98 P99 I109 H110 S111 H115 W117 F15 W27 F30 Y37 P38 I48 H49 S50 H54 W56
External links
PDB RCSB:8p0f, PDBe:8p0f, PDBj:8p0f
PDBsum8p0f
PubMed
UniProtP40337|VHL_HUMAN von Hippel-Lindau disease tumor suppressor (Gene Name=VHL)

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