Structure of PDB 8ozi Chain D

Receptor sequence

>8oziD (length=473) Species: 429344 (Maribacter polysiphoniae) [Search protein sequence]

MKELIYIEEPKILFAHGQKCTDARDGLALFGPLNNLYGIKSGVIGTKQGL
KIFRDYLDHIQKPIYNSNSITRPMFPGFEAVFDCKWESTGITFKEVTNED
IGKFLYNSSTHKRTYDLVSLFIDKIISANKNEDENVDVWFVIVPDEIYKY
CRPNSVLPKEMVQTTYNYDAQFHDQFKARLLKHTIPTQIFRESTLAWRDF
KNAFGLPIRDFSKIEGHLAWTISTAAFYKAGGKPWKLSDVRNGVCYLGLV
YKKVEKSKNPRNACCAAQMFLDNGDGTVFKGEVGPWYNPKNGQYHLEPKE
AKALLSQSLQSYKEQIGEYPKEVFIHAKTRFNHQEWDAFLEVTPKETNLV
GVTISKTKPLKLYKTEGDYTILRGNAYVVNERSAFLWTVGYVPKIQTALS
MEVPNPLFIEINKGEADIKQVLKDILSLTKLNYNACIFADGEPVTLRFAD
KIGEILTASTDIKTPPLAFKYYI

3D structure

PDB

8ozi Activation mechanism of a short argonaute-TIR prokaryotic immune system.

Chain

Resolution

3.22 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	D	Y148 Q205 H207 Q222 I223 F224 R225 T228 R243 F245 L252 T255 G326 K395 M435 E436 N468 A469 D474 G475 R481 I507	Y148 Q171 H173 Q188 I189 F190 R191 T194 R209 F211 L218 T221 G292 K361 M401 E402 N434 A435 D440 G441 R447 I473
BS02	dna	D	R72 P153 N154 F245 K247 I248 H251 Y285 K286 K287 Y328 T363 R364	R72 P153 N154 F211 K213 I214 H217 Y251 K252 K253 Y294 T329 R330

Gene Ontology

	Molecular Function
GO:0003676	nucleic acid binding

View graph for
Molecular Function

External links

PDB	RCSB:8ozi, PDBe:8ozi, PDBj:8ozi
PDBsum	8ozi
PubMed	37467330
UniProt	A0A316E3U6

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