Structure of PDB 8owm Chain D

Receptor sequence
>8owmD (length=412) Species: 3702 (Arabidopsis thaliana) [Search protein sequence]
AMNALAATNRNFRHASRILGLDSKIERSLMIPFREIKVECTIPKDDGTLV
SYIGFRVQHDNARGPMKGGIRYHPEVDPDEVNALAQLMTWKTAVADIPYG
GAKGGIGCSPRDLSLSELERLTRVFTQKIHDLIGIHTDVPAPDMGTNAQT
MAWILDEYSKFHGHSPAVVTGKPIDLGGSLGREAATGRGVVFATEALLAE
YGKSIQGLTFVIQGFGNVGTWAAKLIHEKGGKVVAVSDITGAIRNPEGID
INALIKHKDATGSLNDFNGGDAMNSDELLIHECDVLIPCALGGVLNKENA
GDVKAKFIVEAANHPTDPDADEILSKKGVIILPDIYANAGGVTVSYFEWV
QNIQGFMWEEEKVNLELQKYMTRAFHNIKTMCHTHSCNLRMGAFTLGVNR
VARATQLRGWEA
3D structure
PDB8owm Structural and functional studies of Arabidopsis thaliana glutamate dehydrogenase isoform 2 demonstrate enzyme dynamics and identify its calcium binding site.
ChainD
Resolution1.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.4.1.3: glutamate dehydrogenase [NAD(P)(+)].
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 NAD D R70 D142 M143 R181 T185 F214 G215 N216 V217 D237 I238 C288 A289 A311 N312 N337 R71 D143 M144 R182 T186 F215 G216 N217 V218 D238 I239 C289 A290 A312 N313 N338
BS02 U5C D K66 G68 M87 K90 K102 A140 N312 S344 K67 G69 M88 K91 K103 A141 N313 S345
BS03 CA D S27 I30 S28 I31
Gene Ontology
Molecular Function
GO:0004352 glutamate dehydrogenase (NAD+) activity
GO:0004353 glutamate dehydrogenase [NAD(P)+] activity
GO:0004354 glutamate dehydrogenase (NADP+) activity
GO:0005507 copper ion binding
GO:0005524 ATP binding
GO:0008270 zinc ion binding
GO:0016491 oxidoreductase activity
GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor
GO:0050897 cobalt ion binding
Biological Process
GO:0006520 amino acid metabolic process
Cellular Component
GO:0000325 plant-type vacuole
GO:0005739 mitochondrion
GO:0005794 Golgi apparatus
GO:0005886 plasma membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8owm, PDBe:8owm, PDBj:8owm
PDBsum8owm
PubMed37478728
UniProtQ38946|DHE2_ARATH Glutamate dehydrogenase 2 (Gene Name=GDH2)

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