Structure of PDB 8oqp Chain D

Receptor sequence
>8oqpD (length=402) Species: 83332 (Mycobacterium tuberculosis H37Rv) [Search protein sequence]
SEEAFIYEAIRTPRGKQKNGSLHEVKPLSLVVGLIDELRKRHPDLDENLI
SDVILGCVSPVGDQGGDIARAAVLASGMPVTSGGVQLNRFCASGLEAVNT
AAQKVRSGWDDLVLAGGVESMSRVPMGSDGGAMGLDPATNYDVMFVPQSI
GADLIATIEGFSREDVDAYALRSQQKAAEAWSGGYFAKSVVPVRDQNGLL
ILDHDEHMRPDTTKEGLAKLKPAFEGLAALGGFDDVALQKYHWVEKINHV
HTGGNSSGIVDGAALVMIGSAAAGKLQGLTPRARIVATATSGADPVIMLT
GPTPATRKVLDRAGLTVDDIDLFELNEAFASVVLKFQKDLNIPDEKLNVN
GGAIAMGHPLGATGAMILGTMVDELERRNARRALITLCIGGGMGVATIIE
RV
3D structure
PDB8oqp Substrate specificity and conformational flexibility properties of the Mycobacterium tuberculosis beta-oxidation trifunctional enzyme.
ChainD
Resolution2.18 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.1.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 VXZ D E9 K189 T281 R283 E8 K188 T280 R282
BS02 VXZ D D47 E48 N49 G78 M79 P80 D46 E47 N48 G77 M78 P79
BS03 VXZ D R378 R379 R377 R378
BS04 VXZ D R382 E401 R402 R381 E400 R401
Gene Ontology
Molecular Function
GO:0016746 acyltransferase activity
GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups
Cellular Component
GO:0005886 plasma membrane
GO:0009274 peptidoglycan-based cell wall

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Molecular Function
View graph for
Cellular Component
External links
PDB RCSB:8oqp, PDBe:8oqp, PDBj:8oqp
PDBsum8oqp
PubMed39012716
UniProtO53871|Y0859_MYCTU Putative acyltransferase Rv0859 (Gene Name=fadA)

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