Structure of PDB 8oop Chain D

Receptor sequence
>8oopD (length=441) Species: 209285 (Thermochaetoides thermophila) [Search protein sequence]
LIAAHSHIRGLGVDADTLEPRPSSQGLVGQEKARKAAAVVLEMIKQGKIA
GRAVLIAGPPSTGKTAIAMGMAQSLGQDVPFTTLAASEIFSLEMSKTEAL
TQAFRKSIGVRIKEESEIMEGEVVEIQIDRSVTGGAKQGKLTIKTTDMEA
IYDMGSKMIDAMTKERVMAGDIISIDKSSGKITKLGRSYARSRDYDAMGV
DTKFLQCPEGELQKRKEVVHTVSLHEIDVINSRTQGFLALFSGDTGEIRS
EIRDQINTKVAEWKEEGKAEIVPGVLFIDEVHMLDIECFSYINRALESDL
APIVIMASNRGVSRIRGTDYKSPHGLPLDFLDRVVIINTHPYTPDELRQI
LSIRAQEEEVDLTPDALALLTKIGQEAGLRYASNLITTSQLIAAKRRAKQ
VGVEDVQRSFKLFYDPARSVRFVQESEKRLIGNDGVVDFSY
3D structure
PDB8oop Hexasome-INO80 complex reveals structural basis of noncanonical nucleosome remodeling.
ChainD
Resolution2.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.4.12: DNA helicase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ADP D A23 H24 H26 L46 V47 S80 G82 K83 T84 A85 Y361 L398 R399 A4 H5 H7 L27 V28 S61 G63 K64 T65 A66 Y342 L379 R380
Gene Ontology
Molecular Function
GO:0003678 DNA helicase activity
GO:0004386 helicase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0008094 ATP-dependent activity, acting on DNA
GO:0016787 hydrolase activity
GO:0016887 ATP hydrolysis activity
Biological Process
GO:0000492 box C/D snoRNP assembly
GO:0006281 DNA repair
GO:0006325 chromatin organization
GO:0006338 chromatin remodeling
GO:0006357 regulation of transcription by RNA polymerase II
GO:0032508 DNA duplex unwinding
Cellular Component
GO:0000812 Swr1 complex
GO:0005634 nucleus
GO:0031011 Ino80 complex
GO:0035267 NuA4 histone acetyltransferase complex
GO:0097255 R2TP complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8oop, PDBe:8oop, PDBj:8oop
PDBsum8oop
PubMed37384673
UniProtG0RYC2

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